Nicotinamide Riboside Pro 500 + 250 mg TMG per serving - 60 capsules

Energize Your Cells with NR: The Original NAD+ Booster*

• Rapidly increases NAD+ levels*^1-3,5,6,8
• Optimizes mitochondrial performance*^1-3,5,6
• Enhances cellular energy*^1-3,5,6
• Supports DNA repair & genomic integrity*^1-3,5,6
• Helps combat the aging process*^1,3,4,6

Nicotinamide Riboside (NR) is one of the most exciting breakthroughs in longevity science. As a potent vitamin B3 derivative and direct NAD⁺ precursor, NR helps revitalize cellular energy—promoting healthy aging and lasting vitality.*^1,3,6

What Makes Ours Better?

• The Gold Standard: Nicotinamide Riboside (NR) is the ultimate NAD+ precursor, serving as an essential building block in the NAD+ synthesis pathway*^1,3,4
• Scientifically Supported: A form of vitamin B3, NR that has undergone extensive clinical testing, demonstrating both efficacy and a strong safety profile*^1,3,5,6,8
• 37 Trillion Benefits: NAD+ fuels energy production in trillions of cells, supporting the health and function of every vital organ in the body.*^1,3,6,7
• Rapid Results: NR starts boosting NAD+ levels within 24 hours, with substantial increases observed over days to weeks in a dose-dependent manner*^1,3,6,8

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Why Choose ProHealth?

• Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
• Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
• Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
• Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
• 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

Cellular Energy Starts Here

NAD⁺ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell of your body, essential for converting nutrients into energy, activating DNA-repair enzymes (PARPs), and regulating sirtuins—proteins that influence gene expression and longevity. As a cornerstone of cellular metabolism, NAD⁺ supports energy production, DNA integrity, and healthy aging.*^1,3-5,6

By middle age, NAD⁺ levels in some tissues can drop by up to 50%, slowing down cellular repair and metabolic efficiency. One of the most effective ways to maintain NAD⁺ is with Nicotinamide Mononucleotide (NMN)—a clinically studied form of vitamin B3 that supports the body’s natural NAD⁺ production pathways, helping you feel energized, resilient, and more youthful as you age.*^1,3,5,6

Which is Better: NR or NMN?

NR (Nicotinamide Riboside) and NMN (Nicotinamide Mononucleotide) are two of the most effective NAD+ boosters, but they differ in their biochemical pathways and potential benefits.*

NR shares a similar structure to NMN, but NMN contains an additional phosphate group, making it a larger molecule. This extra phosphate prevents NMN from crossing cell membranes and requires it to be converted into NR before it can enter cells. In contrast, NR is smaller and can easily pass through cell membranes.

Once inside the cell, NR is converted into NMN and subsequently into NAD+ through a series of enzymatic reactions.

Although direct comparison studies between NMN and NR are currently lacking, both have demonstrated effectiveness in raising NAD+ levels and offering similar cellular support. However, NMN stands out in preclinical and clinical research for its unique effects on exercise performance, biological age, and metabolic regulation.*^1,3,4,6

Power Up Your Cells with NR*

Rebuild Your Body’s NAD+ Supply—Daily*
To maintain peak performance, your body requires a steady supply of NAD+. With NMN, you can effortlessly and continuously support your NAD+ levels. Research demonstrates that supplementing with NMN can elevate NAD+ levels in a dose-dependent manner, meaning higher doses yield greater increases in NAD+ concentrations.*^1,3,6,8

Fuel Cellular Energy Production*
NAD+ plays a vital role in converting food into usable energy at the cellular level. With NMN, you can optimize ATP production, leading to enhanced energy availability throughout the body. This boost in cellular energy not only supports physical performance but also contributes to enhanced quality of life.*^1,3,6

Target All 12 Hallmarks of Aging*
As we age, NAD+ levels naturally decline, making replenishment essential to support core longevity processes. NAD+ targets the root causes of aging, fueling essential enzymes like PARPs, which repair DNA and maintain cellular integrity, and activating Sirtuins, which regulate gene expression, inflammation, and stress response—key contributors to healthy aging.*^1,3,4,6

Formulas You Can Feel!
ProHealth offers the world’s most comprehensive collection of NAD⁺-boosting supplements. From foundational ingredients like NR and NMN to next-generation compounds such as NMNH and Apigenin, our lineup spans every major pathway involved in NAD⁺ production and preservation. With multiple delivery forms, clinically studied ingredients, and advanced formulations designed to target energy, metabolism, brain health, and longevity, ProHealth is the global leader in NAD⁺ support—trusted by health seekers, researchers, and practitioners alike.

Ingredient info

• Nicotinamide Riboside (NR): A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*

References:

1. Orr ME et al. GeroScience. 2024;46(1):665-682.
2. Mehmel M et al. I 2020;12(6):1616.
3. Nascimento EBM et al. J Clin Endocrinol Metab. 2021;106(5):1437-1447.
4. Vreones M et al. Aging Cell. 2023;22(1):e13754.
5. Elhassan YS et al. Cell Rep. 2019;28(7):1717-1728.e6.
6. Martens CR et al. Nat Commun. 2018;9(1):1286.
7. Damgaard MV et al. Sci Adv. 2023;9(29):eadi4862.
8. Trammell SAJ et al. Nat Commun. 2016;7(1):12948.